CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14936
Family Name Thromboxane-A synthase inhibitor (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z)-5-carboxypent-2-enyl]-4-(2-hydroxyphenyl)-1,3-dioxan-2-yl]pentoxy]phenyl]-7-pyridin-3-ylhept-6-enoic acid family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00431163 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 105
Class Class 1002

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Renin Inhibitor CP-305202 Family 9 30
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Leukotriene B4 receptor 1 ligand AGN-PC-04XM3V family 3 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase inhibit... 2 24
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 1 18
Thromboxane A2 receptor and Thromboxane-A synthase ligand Ici ... 3 17
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5... 2 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Thromboxane-A synthase and Thromboxane A2 receptor ligand (Z)-... 2 10
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 4 0


External ID

Functional Category

Molecule Name

CFAMM00431163 CHEMBL297385 Bioactive (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z)-5-carboxypent-2-enyl]-4-(2-hydroxyphenyl)-1,3-dioxan-2-yl]pentoxy]phenyl]-7-pyridin-3-ylhept-6-enoic acid
CFAMM00431169 CHEMBL42677 Bioactive (E)-7-[3-[[4-[(2S,4S,5R)-5-[(Z)-5-carboxypent-2-enyl]-4-(2-hydroxyphenyl)-1,3-dioxan-2-yl]phenyl]methoxy]phenyl]-7-pyridin-3-ylhept-6-enoic acid
CFAMM00431167 CHEMBL291167 Bioactive (E)-7-[4-[6-[(2S,4S,5R)-5-[(Z)-5-carboxypent-2-enyl]-4-(2-hydroxyphenyl)-1,3-dioxan-2-yl]-6-methylheptyl]phenyl]-7-pyridin-3-ylhept-6-enoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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