CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14957
Family Name Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydroxy-2-(4-phenoxyphenyl)sulfonyl-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00381445 Functional Category Bioactive
Superfamily Disintegrin and Stromelysin-1 Binder Superfamily
Class Class 44

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
Indeglitazar family 3 39
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Integrin beta-3 Inhibitor L-756568 Family 8 59
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 20 37
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 3
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (3S,... 1 16
Disintegrin and metalloproteinase domain-containing protein 17... 44 12
Collagenase 3 and Interstitial collagenase inhibitor (2R,5R)-N... 4 1
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
Macrophage metalloelastase inhibitor (2S)-3-methyl-2-[[8-[3-(t... 2 6
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
Substance-P receptor ligand AGN-PC-01VLKE family 9 11
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 3
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Gonadotropin-releasing hormone receptor ligand 2-[2-(4-methoxy... 1 1
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Disintegrin and metalloproteinase domain-containing protein 17... 9 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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