CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14972
Family Name Thromboxane-A synthase and Thromboxane A2 receptor ligand (Z)-7-[(2S,3S,4S)-4-[(4-phenylphenyl)methoxy]-2-pyridin-3-ylthiolan-3-yl]hept-4-enoic acid family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00431453 Functional Category Bioactive
Superfamily Thromboxane-A synthase and Pol polyprotein Binder Superfamily
Class Class 272

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 18 17
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase inhibit... 2 24
5-hydroxytryptamine receptor 1D ligand SureCN7253308 family 2 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand (Z)-... 13 5
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 1 18
Sodium/glucose cotransporter 2 inhibitor SureCN1405451 family 4 12
Thromboxane-A synthase inhibitor (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z... 3 9
Thromboxane-A synthase inhibitor (Z)-6-[2-[2-(benzenesulfonyl)... 2 0
Sodium/glucose cotransporter 2 inhibitor (2S,3R,4R,5S,6R)-2-[5... 1 2
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 2 2


External ID

Functional Category

Molecule Name

CFAMM00431453 CHEMBL292331 Bioactive (Z)-7-[(2S,3S,4S)-4-[(4-phenylphenyl)methoxy]-2-pyridin-3-ylthiolan-3-yl]hept-4-enoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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