CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14982
Family Name Pol polyprotein and Protease inhibitor 161186-51-2 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00186876 Functional Category Bioactive
Superfamily Protease and Pol polyprotein Binder Superfamily
Class Class 876

Cousin Family NamesSeedsMembers
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
Epidermal Growth Factor family 111 209
Insulin receptor Ligand Insulin, Porcine Family 61 205
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Renin Inhibitor Remikiren Family 100 126
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Eluxadoline family 4 85
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Renin Inhibitor Enalkiren Family 56 44
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
Pol polyprotein and Protease inhibitor 161186-52-3 family 3 3
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 18
Pol polyprotein inhibitor AC1LAQE0 family 13 4
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Pol polyprotein inhibitor (2S)-4-(1H-benzimidazol-2-ylmethyl)-... 1 0
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 0
Pol polyprotein and Renin inhibitor U-75875 family 12 1
Pol polyprotein inhibitor N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimi... 5 4
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 2 8
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[4-[4-[(... 9 7
Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Pol polyprotein inhibitor AC1LAQDX family 3 0
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431518 CHEMBL435379 Bioactive tert-butyl N-[(2S,3R,4R)-5-[[1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxobutan-2-yl]amino]-3-hydroxy-4-[(4-methoxyphenyl)methylamino]-5-oxo-1-phenylpentan-2-yl]carbamate
CFAMM00431517 CHEMBL292789 Bioactive AC1NS2N6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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