CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14986
Family Name Insulin-like growth factor-binding protein 3 inhibitor (1E)-1-[[4-(3,5-dichlorophenoxy)-3-fluorophenyl]-hydroxymethylidene]-6,7-dioxo-2H-isoquinoline-3-carboxylic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00431551 Functional Category Bioactive
Superfamily Prelamin-A/C and Cyclin-dependent kinase 5 Binder Superfamily
Class Class 2976

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Family 5 14
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 15 28
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Insulin-like growth factor-binding protein 4 and Insulin-like ... 4 44
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
Cellular tumor antigen p53 inhibitor CHEMBL1395699 family 1 30
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431550 CHEMBL56740 Bioactive (1E)-1-[[3-fluoro-4-(4-methylphenoxy)phenyl]-hydroxymethylidene]-6,7-dioxo-2H-isoquinoline-3-carboxylic acid
CFAMM00431551 CHEMBL292841 Bioactive (1E)-1-[[4-(3,5-dichlorophenoxy)-3-fluorophenyl]-hydroxymethylidene]-6,7-dioxo-2H-isoquinoline-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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