CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14993
Family Name Neutrophil elastase inhibitor 1-[(2S)-2-[(4-methoxyphenyl)sulfonylamino]-3-methylbutanoyl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)pyrrolidine-2-carboxamide family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00431634 Functional Category Bioactive
Superfamily Neutrophil elastase Binder Superfamily
Class Class 589

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
Cathepsin K inhibitor SureCN6578603 family 1 3
Cathepsin K and Cathepsin S inhibitor SureCN8247244 family 2 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 14 0
Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-... 7 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Disintegrin and metalloproteinase domain-containing protein 17... 4 2
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Macrophage metalloelastase and Collagenase 3 inhibitor (2S)-N-... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431634 CHEMBL293062 Bioactive 1-[(2S)-2-[(4-methoxyphenyl)sulfonylamino]-3-methylbutanoyl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)pyrrolidine-2-carboxamide
CFAMM00431630 CHEMBL66579 Bioactive (2S)-1-[(2S)-2-[(4-methoxyphenyl)sulfonylamino]-3-methylbutanoyl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)pyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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