CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14994
Family Name Cyclin-dependent kinase 2 and Vascular endothelial growth factor receptor 2 ligand pyrrollylactone indolinone driv. 15f family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00431638 Functional Category Bioactive
Superfamily Tyrosine-protein phosphatase non-receptor type 1 Ligand 6-(oxalyl-amino)-1h-indole-5-carboxylic Acid Superfamily
Class Class 1941

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Tyrosine-protein phosphatase non-receptor type 1 Ligand 6-(oxa... 1 5
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
5-hydroxytryptamine receptor 3A Ligand 3alpha-(1'-methyl-2'-in... 2 17
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 3 4
Receptor-type tyrosine-protein kinase FLT3 and Vascular endoth... 4 4
Renin inhibitor [(2S,4S,5S,7R)-4-amino-8-(butylamino)-5-hydrox... 3 1
Survival motor neuron protein and Menin inhibitor CHEMBL130937... 1 7
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 5
RAC-beta serine/threonine-protein kinase inhibitor SureCN57283... 2 0
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Leucine-rich repeat serine/threonine-protein kinase 2 and Vasc... 1 1
Hepatocyte growth factor receptor and Protein-tyrosine kinase ... 2 15
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Glycogen synthase kinase 3 beta and Dual specificity tyrosine-... 1 6
Caspase-1 inhibitor (3S)-5-[2-(1H-indol-3-yl)acetyl]oxy-4-oxo-... 1 0
Calcium/calmodulin-dependent protein kinase type II subunit de... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431638 CHEMBL293068 Bioactive pyrrollylactone indolinone driv. 15f

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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