CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14996
Family Name Sodium-dependent serotonin transporter inhibitor (2S)-1-[(2S,4R)-4-(4-chloro-1-benzothiophen-2-yl)-2-methylpiperidin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00431639 Functional Category Bioactive
Superfamily Sodium-dependent serotonin transporter and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 24

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 36 18
Sodium-dependent serotonin transporter inhibitor 4-[(2S)-2-hyd... 4 0
Sodium-dependent serotonin transporter inhibitor SureCN6575591... 2 0
RAC-alpha serine/threonine-protein kinase inhibitor N-[(2S)-1-... 2 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0


External ID

Functional Category

Molecule Name

CFAMM00431641 CHEMBL79151 Bioactive (2S)-1-[(2S,4R)-4-(5-chloro-1-benzothiophen-2-yl)-2-methylpiperidin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol
CFAMM00431639 CHEMBL310402 Bioactive (2S)-1-[(2S,4R)-4-(4-chloro-1-benzothiophen-2-yl)-2-methylpiperidin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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