CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14997
Family Name Kappa-type opioid receptor and Mu-type opioid receptor ligand 3-(5-chloro-2-methoxyphenyl)-1-(1-phenyl-2-pyrrolidin-1-ylethyl)pyridin-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00431642 Functional Category Bioactive
Superfamily Vasopressin V2 receptor and Vasopressin V1a receptor Binder Superfamily 3
Class Class 893

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Nemonapride Family 70 283
Insulin receptor Ligand Meglitinides Family 9 25
C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Kappa-type opioid receptor Ligand ICI-204448 Family 7 26
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Urotensin-2 receptor Ligand SB-436811 Family 6 71
D(2) dopamine receptor Ligand Epidepride Family 31 66
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 10 5
D(2) dopamine receptor ligand 2-bromo-3-chloro-N-[[(2S)-1-ethy... 1 1
D(2) dopamine receptor ligand 2-chloro-3-ethyl-N-[[(2S)-1-ethy... 3 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 4
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 6
Histamine H1 receptor and Histamine H3 receptor ligand 4-[(4-m... 3 6
Histamine H3 receptor ligand 1-methyl-5-[4-[3-[(2R)-2-methylpy... 5 5
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Substance-K receptor ligand AGN-PC-074GE0 family 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 2
Kappa-type opioid receptor ligand N-[(1S)-2-[(3S)-3-hydroxypyr... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431642 CHEMBL293143 Bioactive 3-(5-chloro-2-methoxyphenyl)-1-(1-phenyl-2-pyrrolidin-1-ylethyl)pyridin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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