CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM14998
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor (3R,6S,12S)-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-5,8,11,14,17-pentaoxo-18-[4-(trifluoromethyl)phenyl]-1-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00431649 Functional Category Bioactive
Superfamily Maraciclatide Superfamily
Class Class 1222

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Oxytocin receptor Ligand Oxytocin Family 30 182
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Growth hormone-releasing hormone receptor ligand polypeptide ... 14 34
Atrial natriuretic peptide receptor 1 Ligand Nesiritide Family 6 111
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Thymopentin family 20 133
Thymosin Beta-4 family 8 30
Maraciclatide family 2 0
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Neuromedin-K receptor Ligand Senktide Family 15 22
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Integrin beta-3 Inhibitor SKF-107260 Family 5 8
Nociceptin receptor Ligand Fggftgcrkscrk Family 10 0
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Beta-secretase 1 Inhibitor KMI-172 Family 3 0
Chymase Inhibitor Chymostatin Family 2 3
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Genome polyprotein Inhibitor Acasp-glu-dif-glu-cha-cys Family 13 17
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 13 17
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-b... 3 4
NS3 and Non-structural protein 4A inhibitor (4S)-4-[[(2S)-3-ca... 1 1
Plasminogen inhibitor (2S)-2-acetamido-5-(diaminomethylideneam... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,1... 8 2
Integrin alpha-V and Integrin beta-5 inhibitor 2-[(2S,5R,8S,11... 2 1
Bcl-2-like protein 1 inhibitor CHEMBL501005 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431643 CHEMBL444306 Bioactive (3R,6S,12S)-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-5,8,11,14,17-pentaoxo-18-(4-phenylphenyl)-1-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid
CFAMM00431649 CHEMBL293231 Bioactive (3R,6S,12S)-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-5,8,11,14,17-pentaoxo-18-[4-(trifluoromethyl)phenyl]-1-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid
CFAMM00431648 CHEMBL65442 Bioactive (3R,6S,12S)-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-5,8,11,14,17-pentaoxo-18-[3-(trifluoromethyl)phenyl]-1-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid
CFAMM00431647 CHEMBL62969 Bioactive (3R,6S,12S)-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-18-naphthalen-1-yl-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid
CFAMM00431646 CHEMBL63082 Bioactive (3R,6S,12S,15R)-15-benzyl-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-1,5,8,11,14,17-hexaoxo-1$l^{4}-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid
CFAMM00431645 CHEMBL304675 Bioactive (3R,6S,12S,15S)-15-benzyl-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-1,5,8,11,14,17-hexaoxo-1$l^{4}-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid
CFAMM00431644 CHEMBL431952 Bioactive (3R,6S,12S)-6-(carboxymethyl)-12-[3-(diaminomethylideneamino)propyl]-5,8,11,14,17-pentaoxo-18-[2-(trifluoromethyl)phenyl]-1-thia-4,7,10,13,16-pentazacyclooctadecane-3-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27037 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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