CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15003
Family Name 72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7241427 family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00305661 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Collagenase 3 Binder Superfamily
Class Class 3090

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Trypsin Inhibitor Benzamidrazone Analogue Family 2 6 38
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 45
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Cathepsin K inhibitor SureCN6578603 family 1 3
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Integrin beta-3 and Integrin alpha-IIb inhibitor (2R)-2-(benze... 4 13
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Pol polyprotein inhibitor AC1LA9K7 family 7 23
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Pol polyprotein inhibitor AC1NQUJL family 10 11
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 8
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-ethy... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Collagenase 3 and 72 kDa type IV collagenase inhibitor SureCN1... 8 50
Collagenase 3 and A disintegrin and metalloproteinase with thr... 10 19
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 1
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Thromboxane A2 receptor ligand 3-[3-[2-[(4-chlorophenyl)sulfon... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 1 6
Carbonic anhydrase 2 inhibitor benzyl 2-[[2-[[(2S)-3-phenyl-2-... 2 9
Collagenase 3 inhibitor (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-... 34 1
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 4 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 2 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Integrin alpha-V inhibitor (2R)-3-[(2-methoxybenzoyl)amino]-2-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431666 CHEMBL309067 Bioactive (3R)-3-[[(2S)-3-cyclohexyl-1-oxo-1-[2-(4-sulfamoylphenyl)ethylamino]propan-2-yl]carbamoyl]-6-(4-methoxyphenyl)hexanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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