CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15007
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butylsulfonylamino)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]propanoic acid family
No. of Seeds 8 No. of Other Members 6
Family Centroid CFAMM00431709 Functional Category Bioactive
Superfamily Integrin beta-3 and Integrin alpha-IIb Binder Superfamily 8
Class Class 745

Cousin Family NamesSeedsMembers
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Type-1 angiotensin II receptor ligand AGN-PC-04X45B family 9 12
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6016173 f... 10 15
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-3-[[3-ox... 2 0
Carbonic anhydrase 2 inhibitor SureCN9373983 family 5 0
Carbonic anhydrase 2 inhibitor AGN-PC-07C00S family 4 1
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-[(4-ch... 1 0


External ID

Functional Category

Molecule Name

CFAMM00431713 CHEMBL312113 Bioactive (2S)-2-(butylsulfonylamino)-3-[[2-(2-piperidin-4-ylethyl)thieno[3,2-b]thiophene-5-carbonyl]amino]propanoic acid
CFAMM00431704 CHEMBL78503 Bioactive (2S)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]-2-(thiophen-2-ylsulfonylamino)propanoic acid
CFAMM00431712 CHEMBL78517 Bioactive (2S)-3-[[2-(2-piperidin-4-ylethyl)thieno[3,2-b]thiophene-5-carbonyl]amino]-2-(thiophen-2-ylsulfonylamino)propanoic acid
CFAMM00431703 CHEMBL79211 Bioactive (2S)-2-(2-ethoxyethylsulfonylamino)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]propanoic acid
CFAMM00431711 CHEMBL78570 Bioactive (2S)-2-(benzenesulfonamido)-3-[[2-(2-piperidin-4-ylethyl)thieno[3,2-b]thiophene-5-carbonyl]amino]propanoic acid
CFAMM00431709 CHEMBL80381 Bioactive (2S)-2-(butylsulfonylamino)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]propanoic acid
CFAMM00431702 CHEMBL80819 Bioactive (2S)-2-(2-ethoxyethylsulfonylamino)-3-[[2-(2-piperidin-4-ylethyl)thieno[3,2-b]thiophene-5-carbonyl]amino]propanoic acid
CFAMM00431707 CHEMBL293601 Bioactive (2S)-2-(benzenesulfonamido)-3-[[2-(2-piperidin-4-ylethyl)thieno[2,3-b]thiophene-5-carbonyl]amino]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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