CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15031
Family Name Capsid scaffolding protein inhibitor AC1O583J family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00431846 Functional Category Bioactive
Superfamily Prostaglandin G/H synthase 2 and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 2554

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Tacrine Family 12 515
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Kinesin-like protein KIF11 Inhibitor 2-(trifluoromethyl)-9h-ca... 5 0
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 1 3
Metabotropic glutamate receptor 5 Ligand 3-fluoro-5-(2-methylq... 3 2
Prostaglandin G/H synthase 2 Inhibitor 2-(4-(methylsulfonyl)ph... 7 33
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 4 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 5 6
Melanin-concentrating hormone receptor 2 ligand N,N-dimethyl-3... 2 2
Melanin-concentrating hormone receptor 2 and Sodium-dependent ... 2 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
Capsid scaffolding protein inhibitor 1-(benzenesulfonyl)-3-[5-... 3 1


External ID

Functional Category

Molecule Name

CFAMM00431845 CHEMBL293998 Bioactive AC1O583M
CFAMM00431843 CHEMBL442168 Bioactive N-[5-[(E)-2-(8-chloroquinolin-2-yl)ethenyl]naphthalen-2-yl]-1,1,1-trifluoromethanesulfonamide
CFAMM00431842 CHEMBL299278 Bioactive AC1O583S
CFAMM00431848 CHEMBL299043 Bioactive AC1O583V
CFAMM00431846 CHEMBL440297 Bioactive AC1O583J

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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