CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15033
Family Name Beta-3 adrenergic receptor and Beta-2 adrenergic receptor ligand 1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-pyridin-3-yloxypropyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00431853 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 7
Class Class 1200

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 ... 4 5
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
Prothrombin inhibitor AGN-PC-074A4O family 2 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Beta-3 adrenergic receptor ligand N-[2-hydroxy-5-[(1R)-1-hydro... 2 1
Glucose-dependent insulinotropic receptor ligand AGN-PC-07ZCQ6... 2 8
TGF-beta receptor type-1 ligand 2wou family 1 0
Prothrombin inhibitor tert-butyl N-[2-[3-[bis(benzenesulfonyl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431866 CHEMBL68408 Bioactive 1-[4-[[4-[2-[[(2S)-3-(6-aminopyridin-3-yl)oxy-2-hydroxypropyl]amino]ethyl]phenyl]sulfamoyl]phenyl]-3-hexylurea
CFAMM00431853 CHEMBL67015 Bioactive 1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-pyridin-3-yloxypropyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea
CFAMM00431859 CHEMBL64201 Bioactive N-[4-[2-[[(2S)-3-(6-aminopyridin-3-yl)oxy-2-hydroxypropyl]amino]ethyl]phenyl]-4-iodobenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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