CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15040
Family Name Atrial natriuretic peptide receptor 1 and Atrial natriuretic peptide receptor 3 ligand (3S)-4-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-2-methylbutyl]amino]-1-oxopentan-2-yl]amino]-3-[[(2S,3S)-3-methyl-2-[[(2S)-2-[[2-[4-(naphthalene-2-carbonylamino)phenyl]acetyl]amino]propanoyl]amino]pentanoyl]amino]-4-oxobutanoic acid family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00431900 Functional Category Bioactive
Superfamily Integrin beta-3 Inhibitor Lotrafiban Superfamily
Class Class 1675

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Integrin beta-3 Inhibitor SKF-107260 Family 5 8
Integrin beta-3 Inhibitor SB-208651 Family 9 28
Integrin beta-3 Inhibitor Lotrafiban Family 5 1
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Caspase-1 inhibitor CHEMBL114791 family 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 1
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 3 5
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Prothrombin and Coagulation factor X inhibitor AC1NDIV9 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00431900 CHEMBL294263 Bioactive (3S)-4-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-2-methylbutyl]amino]-1-oxopentan-2-yl]amino]-3-[[(2S,3S)-3-methyl-2-[[(2S)-2-[[2-[4-(naphthalene-2-carbonylamino)phenyl]acetyl]amino]propanoyl]amino]pentanoyl]amino]-4-oxobutanoic acid
CFAMM00431899 CHEMBL58588 Bioactive (3S)-4-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-2-methylbutyl]amino]-1-oxopentan-2-yl]amino]-3-[[(2S,3S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[4-(naphthalene-2-carbonylamino)phenyl]acetyl]amino]pentanoyl]amino]-3-methylpentanoyl]amino]-4-oxobutanoic acid
CFAMM00431898 CHEMBL61383 Bioactive (3S)-3-[[(2S,3S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[4-(naphthalene-2-carbonylamino)phenyl]acetyl]amino]pentanoyl]amino]-3-methylpentanoyl]amino]-4-[[(2S)-1-[[(2S)-2-methylbutyl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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