CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15042
Family Name Sodium-dependent serotonin transporter and Transporter inhibitor CHEMBL57281 family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00431904 Functional Category Bioactive with Natural Product
Superfamily Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fluorobenzoate Superfamily
Class Class 237

Cousin Family NamesSeedsMembers
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 1 6
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 8 30
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Sodium-dependent serotonin transporter and Transporter inhibit... 6 9
Transporter and Sodium-dependent serotonin transporter inhibit... 8 6
Sodium-dependent dopamine transporter inhibitor ethyl (3S,4S)-... 6 11
Sodium-dependent serotonin transporter and Transporter inhibit... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 3
Transporter and Sodium-dependent dopamine transporter inhibito... 1 5


External ID

Functional Category

Molecule Name

CFAMM00431905 CHEMBL294376 Bioactive CHEMBL294376
CFAMM00431904 CHEMBL57281 Bioactive CHEMBL57281
CFAMM00431902 CHEMBL58858 Bioactive CHEMBL58858
CFAMM00431901 CHEMBL58392 Bioactive CHEMBL58392

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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