CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15044
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor methyl (2S)-2-[[3-[[(4-cyanophenyl)methyl-[[3-[(4-cyanophenyl)methyl]imidazol-4-yl]methyl]amino]methyl]benzoyl]amino]-4-methylsulfanylbutanoate family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00431911 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta and Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Binder Superfamily 2
Class Class 1170

Cousin Family NamesSeedsMembers
Eluxadoline family 4 85
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 11 22
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 8
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 3... 5 14
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor (2S)-2... 2 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431912 CHEMBL61785 Bioactive (2S)-2-[[3-[[(4-cyanophenyl)methyl-[[3-[(4-cyanophenyl)methyl]imidazol-4-yl]methyl]amino]methyl]benzoyl]amino]-4-methylsulfanylbutanoic acid
CFAMM00431911 CHEMBL294433 Bioactive methyl (2S)-2-[[3-[[(4-cyanophenyl)methyl-[[3-[(4-cyanophenyl)methyl]imidazol-4-yl]methyl]amino]methyl]benzoyl]amino]-4-methylsulfanylbutanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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