CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15049
Family Name Neprilysin inhibitor benzyl (2S)-2-[[2-(sulfanylmethyl)-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]propanoate family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00431922 Functional Category Bioactive
Superfamily Neprilysin and Caspase-3 Binder Superfamily
Class Class 3300

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Ezatiostat family 1 4
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cruzipain Inhibitor WRR-204 Family 18 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Caspase-1 Inhibitor Z-vad-cho Family 8 34
Cathepsin B and Cathepsin S Inhibitor Cbz-ile-leu-ala-leuvsme ... 12 14
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(1-me... 3 8
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(2-th... 2 5
Cathepsin S inhibitor SureCN6857538 family 2 12
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 2 2
Neprilysin and Aminopeptidase N inhibitor benzyl 2-[[(2S)-2-[[... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN63170... 1 1
Peptidyl-prolyl cis-trans isomerase FKBP1A and Peptidyl-prolyl... 4 27
Pol polyprotein inhibitor benzyl N-[(2S,3R)-4-[(3aR,6S,7aS)-6-... 3 2
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Pol polyprotein inhibitor benzyl N-[(2R)-1-[[(1S)-1-[(2R,3S)-3... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Substance-P receptor and Voltage-dependent L-type calcium chan... 1 0
Solute carrier family 12 member 5 inhibitor AGN-PC-07ZCLM family 1 12
Substance-P receptor ligand (3,5-dimethylphenyl)methyl (2S)-2-... 1 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 1-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431922 CHEMBL294536 Bioactive benzyl (2S)-2-[[2-(sulfanylmethyl)-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]propanoate
CFAMM00431921 CHEMBL431957 Bioactive AGN-PC-074DAZ
CFAMM00431920 CHEMBL433492 Bioactive benzyl (2S)-3-methyl-2-[[2-(sulfanylmethyl)-3,4-dihydro-1H-naphthalene-2-carbonyl]amino]butanoate
CFAMM00431919 CHEMBL304233 Bioactive AGN-PC-074DB0

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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