CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15054
Family Name 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor ligand SureCN10562668 family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00159429 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2,5-diphenyl-furan-3-yl)-morpholine Superfamily
Class Class 1685

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Tubulin Inhibitor WR85915 Family 3 15
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Granulocyte colony-stimulating factor receptor Ligand N-(2-mor... 1 24
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Sodium channel protein type 10 subunit alpha and Sodium channe... 2 13
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Histone deacetylase 2 Inhibitor N-(2-amino-5-(furan-2-yl)pheny... 3 7
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 20 9
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 35
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 4 4
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 16 6
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Translocator protein inhibitor N-[(2,5-dimethoxyphenyl)methyl]... 1 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 4 6
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 5 6
5-hydroxytryptamine receptor 1A ligand SureCN10513645 family 9 1
Oxytocin receptor and Vasopressin V1a receptor ligand N-[[5-[4... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 0
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 1 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Neuropeptide Y receptor type 5 ligand 3-dibenzofuran-2-yl-1-[(... 1 2
Huntingtin and Ras-related protein Rab-9A inhibitor CHEMBL1971... 1 1
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 1 0
P2Y purinoceptor 1 inhibitor AGN-PC-080TOG family 4 1
Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand ... 1 0
N-[3-methyl-2-(4-methylbenzoyl)-1-benzofuran-5-yl]benzamide NP... 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00431959 CHEMBL573131 Bioactive (3R)-3-methyl-1-[4-(trifluoromethyl)-1-benzofuran-7-yl]piperazine
CFAMM00431963 CHEMBL61242 Bioactive 1-(6-fluoro-1-benzofuran-7-yl)piperazine
CFAMM00431962 CHEMBL555633 Bioactive AGN-PC-07BZJ9
CFAMM00431960 CHEMBL92242 Bioactive N-[2-[4-(1-benzofuran-7-yl)piperazin-1-yl]ethyl]cyclohexanecarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543