CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15062
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[4-[4-[(1H-benzimidazol-2-ylamino)methyl]piperidin-1-yl]-5-methyl-2-oxopyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid family
No. of Seeds 9 No. of Other Members 7
Family Centroid CFAMM00432032 Functional Category Bioactive
Superfamily Calcitonin gene-related peptide type 1 receptor and Integrin beta-3 Binder Superfamily
Class Class 3274

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Pol polyprotein inhibitor penicillin deriv. 71 family 1 2
Pol polyprotein and Protease inhibitor 161186-52-3 family 3 3
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Pol polyprotein inhibitor N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimi... 5 4
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor 2-[1-[2-[[4-(1H... 2 8
Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-4-[4-[3-(1... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432026 CHEMBL47060 Bioactive (3R)-4-[4-[4-(1H-benzimidazol-2-ylamino)piperidin-1-yl]-5-methyl-2-oxopyrimidin-1-yl]-3-(phenylmethoxycarbonylamino)butanoic acid
CFAMM00432032 CHEMBL44772 Bioactive (2S)-3-[4-[4-[(1H-benzimidazol-2-ylamino)methyl]piperidin-1-yl]-5-methyl-2-oxopyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00432024 CHEMBL44982 Bioactive (3R)-4-[4-[4-[2-(1H-benzimidazol-2-ylamino)ethyl]piperidin-1-yl]-5-methyl-2-oxopyrimidin-1-yl]-3-(phenylmethoxycarbonylamino)butanoic acid
CFAMM00432031 CHEMBL48042 Bioactive (2S)-3-[4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-5-methyl-2-oxopyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00432023 CHEMBL45573 Bioactive (2S)-3-[4-[4-[(1H-benzimidazol-2-ylamino)methyl]piperidin-1-yl]-5-benzyl-2-oxopyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00432021 CHEMBL294953 Bioactive (3R)-4-[4-[3-(1H-benzimidazol-2-ylamino)propylamino]-5-methyl-2-oxopyrimidin-1-yl]-3-(phenylmethoxycarbonylamino)butanoic acid
CFAMM00432034 CHEMBL45327 Bioactive (2S)-3-[4-[4-[(1H-benzimidazol-2-ylamino)methyl]piperidin-1-yl]-2-oxo-5-(2-phenylethyl)pyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00432027 CHEMBL47699 Bioactive (2S)-3-[4-[4-[(1H-benzimidazol-2-ylamino)methyl]piperidin-1-yl]-2-oxo-5-propylpyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid
CFAMM00432033 CHEMBL46333 Bioactive (2S)-3-[4-[4-(1H-benzimidazol-2-ylamino)piperidin-1-yl]-5-methyl-2-oxopyrimidin-1-yl]-2-(phenylmethoxycarbonylamino)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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