CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15065
Family Name Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-aminobutyric acid receptor subunit gamma-2 ligand 10-(4-methyl-1,3-thiazol-2-yl)-12-phenyl-6,7-dihydro-5H-dipyrido[2,3-b:1',3'-d]azepin-9-one family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00432081 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-aminobutyric acid receptor subunit beta-3 Binder Superfamily
Class Class 3370

Cousin Family NamesSeedsMembers
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 13
Metabotropic glutamate receptor 1 ligand AGN-PC-0A9TG5 family 11 10
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 4 10
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 4
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 17
Metabotropic glutamate receptor 5 ligand 2-(2-pyridin-3-ylethy... 1 2
Metabotropic glutamate receptor 5 ligand N-[(2R)-3-hydroxy-3-m... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432079 CHEMBL46567 Bioactive AGN-PC-073P4H
CFAMM00432077 CHEMBL44916 Bioactive AGN-PC-073P8B
CFAMM00432083 CHEMBL295027 Bioactive AGN-PC-073P4G
CFAMM00432082 CHEMBL45110 Bioactive AGN-PC-00GXT4
CFAMM00432081 CHEMBL44533 Bioactive 10-(4-methyl-1,3-thiazol-2-yl)-12-phenyl-6,7-dihydro-5H-dipyrido[2,3-b:1',3'-d]azepin-9-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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