CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15070
Family Name Substance-P receptor and Potassium voltage-gated channel subfamily H member 2 ligand 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(1-oxa-8-azaspiro[4.5]decan-8-yl)-1-phenylcyclohexyl]propanamide family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00401552 Functional Category Bioactive
Superfamily Substance-P receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 3
Class Class 3563

Cousin Family NamesSeedsMembers
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Substance-P receptor Ligand Orvepitant Family 11 46
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 7 3
Substance-P receptor and Potassium voltage-gated channel subfa... 4 7
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Substance-P receptor ligand AGN-PC-073QYE family 6 11
C-C chemokine receptor type 2 ligand (1S,3R)-N-[[3-fluoro-5-(t... 22 27
Substance-P receptor ligand AGN-PC-03I9DJ family 3 0
Substance-P receptor and Potassium voltage-gated channel subfa... 5 1


External ID

Functional Category

Molecule Name

CFAMM00432101 CHEMBL49184 Bioactive 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-[4-(2,2-dimethyloxolan-3-yl)piperidin-1-yl]-1-phenylcyclohexyl]propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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