CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15071
Family Name Pol polyprotein inhibitor AC1L9R8I family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00432102 Functional Category Bioactive
Superfamily Pol polyprotein and Disintegrin Binder Superfamily
Class Class 3076

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Flovagatran family 12 546
Renin Inhibitor CP-80794 Family 16 112
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor RWJ-53419 Family 6 65
Somatostatin receptor type 1 Ligand Des-aa1,2,5-[(nalphame)lys... 16 11
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Disks large homolog 4 Inhibitor N-(3,4-difluorophenyl)propyl-e... 3 0
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Serine/threonine protein phosphatase PP1-alpha 1 catalytic sub... 10 0
Renin inhibitor (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[... 12 1
Renin inhibitor (2S,4S,5S)-N-(4-aminobutyl)-6-cyclohexyl-4-hyd... 32 2
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Renin inhibitor (2S,4S,5S)-N-[3-[[amino-(cyanoamino)methyliden... 7 0
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 11 8
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Pol polyprotein inhibitor AC1L9R8S family 5 4
Beta-secretase 1 and Cathepsin D inhibitor (1R,3S)-N-[(2S,3S)-... 2 25
Pol polyprotein inhibitor benzyl N-[(2S)-1-[[(2S,3S,4R,5S)-3,4... 21 5
Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2
Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4
Renin inhibitor tert-butyl N-[1-[[(3S,6S,7R)-6-(cyclohexylmeth... 14 1
Cathepsin B and Calpain-2 catalytic subunit inhibitor AGN-PC-0... 2 2
Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-0... 3 1
Renin and Cathepsin D inhibitor (3S)-4-[[6-acetamido-2-[[3-nap... 6 26
Renin inhibitor [(2R)-1-[[(2S,3S,5R)-6-(butylamino)-1-cyclohex... 5 4
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 6 1
Pol polyprotein inhibitor Sulfone deriv. 31 family 15 4
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Pol polyprotein inhibitor AC1LADQG family 7 1
Endothelin-converting enzyme 1 and Cathepsin D inhibitor N-[(2... 6 2
Pol polyprotein inhibitor AC1LADII family 12 1
Beta-secretase 1 inhibitor (2S)-2-[(3R)-3-acetamido-3-(2-methy... 3 0
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 3 0
Pol polyprotein inhibitor benzyl N-[(2S)-4-amino-1-[[(2S,3R)-4... 2 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 3
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 5 3
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Renin and Cathepsin D inhibitor ethyl (4S)-5-cyclohexyl-2,2-di... 2 0
Pol polyprotein inhibitor AC1L9R8M family 4 1
Renin inhibitor 2-methylpropyl N-[1-[[1-[[(3R,4S)-1-cyclohexyl... 14 0
Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-h... 2 0
Pol polyprotein inhibitor AC1LA3C0 family 2 18
Pol polyprotein inhibitor Diol-Based HIV-1 protease inhibitor ... 1 0
Pol polyprotein inhibitor AC1LACBC family 2 0
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Pol polyprotein and Pepsin A inhibitor cgp 53820 family 1 1
Pol polyprotein inhibitor methyl (2S)-2-[[(2R,4S,5S)-2-benzyl-... 1 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432102 CHEMBL295345 Bioactive AC1L9R8I

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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