CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15073
Family Name Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-2-ylmethoxy)phenyl]methoxy]-2,3-dihydrochromene-2-carboxylic acid family
No. of Seeds 4 No. of Other Members 17
Family Centroid CFAMM00432126 Functional Category Bioactive with Natural Product
Superfamily Cysteinyl leukotriene receptor 1 and Beta-lactamase Binder Superfamily
Class Class 2015

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Pranlukast Family 21 72
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Leukotriene B4 receptor 1 Ligand SB-201993 Family 5 13
Oestrogen receptor and Estrogen receptor beta Ligand 2-naphtha... 4 51
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 7
Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinoli... 6 15
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Thyroid hormone receptor beta ligand CHEMBL1397256 family 1 12
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[2-butyl-1-[4-(qu... 1 12
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Cysteinyl leukotriene receptor 1 ligand 7-[[3-(quinolin-2-ylme... 7 5
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[(1... 2 0
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-met... 3 0
Arachidonate 5-lipoxygenase-activating protein inhibitor 5-[2-... 7 1
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Acetylcholinesterase and Cholinesterase inhibitor 5-methoxy-7-... 1 18
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 3 5
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Cysteinyl leukotriene receptor 1 ligand 2-[2-[5-[[3-[(E)-2-(6,... 1 8
Testosterone 17-beta-dehydrogenase 3 inhibitor AGN-PC-04XS1Y f... 1 4
Cysteinyl leukotriene receptor 1 ligand 6-bromo-4-oxo-3-(quino... 3 1
Histamine H1 receptor and Histamine H2 receptor ligand SureCN6... 1 3
Histamine H1 receptor and Histamine H2 receptor ligand SureCN5... 3 6
Reverse transcriptase/RNaseH inhibitor 3-[2-(1-benzofuran-2-yl... 1 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 1 0
Integrase and Serine/threonine-protein kinase pim-1 inhibitor ... 3 0
3-quinolin-2-ylchromen-2-one NP ZINC08690002 Family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432116 CHEMBL296097 Bioactive SureCN9636955
CFAMM00432130 CHEMBL46343 Bioactive 4-oxo-6-[[3-(quinolin-2-ylmethoxy)phenyl]methoxy]-2,3-dihydrochromene-2-carboxylic acid
CFAMM00432127 CHEMBL295368 Bioactive 4-oxo-7-[[4-(quinolin-2-ylmethoxy)phenoxy]methyl]-2,3-dihydrochromene-2-carboxylic acid
CFAMM00432126 CHEMBL49449 Bioactive 4-oxo-7-[[3-(quinolin-2-ylmethoxy)phenyl]methoxy]-2,3-dihydrochromene-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26832 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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