CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15078
Family Name Endothelin-1 receptor ligand 2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00432166 Functional Category Bioactive with Natural Product
Superfamily Endothelin-1 receptor Binder Superfamily 2
Class Class 3074

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
Cytochrome P450 3A4 Inhibitor 1,2-diacetoxylycorine Family 4 19
Tubulin beta chain Inhibitor Colchinol Family 3 109
D(2) dopamine receptor and Sodium-dependent dopamine transport... 6 10
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 20
Benzazepines Metabolite N-Methylporphyroxine Family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432167 CHEMBL47868 Bioactive 2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-3,4-dimethoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
CFAMM00432166 CHEMBL295440 Bioactive 2-[(1R,3S)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid
CFAMM00432171 CHEMBL50232 Bioactive 2-[(1R,3R)-1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-5-ethoxy-1,3-dihydroisoindol-2-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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