CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15082
Family Name Disintegrin and metalloproteinase domain-containing protein 17 and 72 kDa type IV collagenase inhibitor (2R)-2-[7-[(3,5-dimethoxyphenyl)methoxy]-1,1-dioxo-4,5-dihydro-3H-1$l^{6},2,5-benzothiadiazepin-2-yl]-N-hydroxy-6-(methanesulfonamido)hexanamide family
No. of Seeds 4 No. of Other Members 17
Family Centroid CFAMM00432190 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 17
Class Class 5093

Cousin Family NamesSeedsMembers
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 20 23
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 8 6
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432190 CHEMBL416306 Bioactive (2R)-2-[7-[(3,5-dimethoxyphenyl)methoxy]-1,1-dioxo-4,5-dihydro-3H-1$l^{6},2,5-benzothiadiazepin-2-yl]-N-hydroxy-6-(methanesulfonamido)hexanamide
CFAMM00432195 CHEMBL454380 Bioactive 2-[7-[(3,5-dimethoxyphenyl)methoxy]-1,1-dioxo-4,5-dihydro-3H-1$l^{6},2,5-benzothiadiazepin-2-yl]-N-hydroxy-6-(methanesulfonamido)hexanamide
CFAMM00432199 CHEMBL52808 Bioactive methyl (5R)-5-[7-[(3,5-dimethoxyphenyl)methoxy]-1,1-dioxo-4,5-dihydro-3H-1$l^{6},2,5-benzothiadiazepin-2-yl]-6-(hydroxyamino)-6-oxohexanoate
CFAMM00432191 CHEMBL295710 Bioactive (2R)-2-[7-[(3,5-dimethoxyphenyl)methoxy]-1,1-dioxo-4,5-dihydro-3H-1$l^{6},2,5-benzothiadiazepin-2-yl]-N-hydroxy-3-methylbutanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27634 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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