CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15085
Family Name Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-(3-imidazol-1-ylpropyl)-5-[[(2S)-2-[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]oxyhexanoyl]amino]-2-propan-2-ylhexanamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00432250 Functional Category Bioactive
Superfamily Renin Binder Superfamily 10
Class Class 1170

Cousin Family NamesSeedsMembers
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
Renin Inhibitor Remikiren Family 100 126
Renin Inhibitor Enalkiren Family 56 44
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Glycylpeptide N-tetradecanoyltransferase Inhibitor SC-58272 Fa... 2 11
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Renin inhibitor propan-2-yl (3R)-2-hydroxy-3-[[(2S)-3-(1H-imid... 4 0
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Renin inhibitor [(2S)-1-[[(2R)-1-[[(2S,3S)-1-cyclohexyl-3-hydr... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432250 CHEMBL295838 Bioactive (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-(3-imidazol-1-ylpropyl)-5-[[(2S)-2-[(2S)-1-[4-(methoxymethoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]oxyhexanoyl]amino]-2-propan-2-ylhexanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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