CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15089
Family Name Gonadotropin-releasing hormone receptor ligand 1-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-[2-[(2S)-piperidin-2-yl]ethoxy]-1H-quinolin-6-yl]-3-pyrazin-2-ylurea family
No. of Seeds 7 No. of Other Members 1
Family Centroid CFAMM00432271 Functional Category Bioactive
Superfamily Gonadotropin-releasing hormone receptor Binder Superfamily 6
Class Class 3306

Cousin Family NamesSeedsMembers
Gonadotropin-releasing hormone receptor ligand 7-chloro-3-(3,5... 28 19
Gonadotropin-releasing hormone receptor ligand 7-chloro-3-(3,5... 1 2
Somatostatin receptor type 2 ligand SureCN4325675 family 3 1
Somatostatin receptor type 2 ligand SureCN4317006 family 10 1
Gonadotropin-releasing hormone receptor ligand 7-chloro-2-oxo-... 11 0
Gonadotropin-releasing hormone receptor ligand SureCN8149168 f... 2 43
Gonadotropin-releasing hormone receptor ligand SureCN8149183 f... 5 0
Gonadotropin-releasing hormone receptor ligand 4-[2-[(2S)-azet... 1 0
Gonadotropin-releasing hormone receptor ligand 7-chloro-3-(3,5... 2 1


External ID

Functional Category

Molecule Name

CFAMM00432271 CHEMBL416651 Bioactive 1-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-[2-[(2S)-piperidin-2-yl]ethoxy]-1H-quinolin-6-yl]-3-pyrazin-2-ylurea
CFAMM00432270 CHEMBL295911 Bioactive 1-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-(2-piperidin-2-ylethoxy)-1H-quinolin-6-yl]-3-pyrimidin-2-ylurea
CFAMM00432269 CHEMBL295917 Bioactive N-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-(2-piperidin-2-ylethoxy)-1H-quinolin-6-yl]pyrazine-2-carboxamide
CFAMM00432268 CHEMBL47895 Bioactive 1-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-[2-[(2S)-piperidin-2-yl]ethoxy]-1H-quinolin-6-yl]-3-pyrimidin-4-ylurea
CFAMM00432274 CHEMBL50433 Bioactive 1-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-(2-piperidin-2-ylethoxy)-1H-quinolin-6-yl]-3-pyrimidin-4-ylurea
CFAMM00432267 CHEMBL46312 Bioactive N-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-[2-[(2S)-piperidin-2-yl]ethoxy]-1H-quinolin-6-yl]pyrazine-2-carboxamide
CFAMM00432273 CHEMBL50283 Bioactive 1-[7-chloro-3-(3,5-dimethylphenyl)-2-oxo-4-(2-piperidin-2-ylethoxy)-1H-quinolin-6-yl]-3-pyrazin-2-ylurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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