CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15099
Family Name Epidermal growth factor receptor ligand AGN-PC-078X7L family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00432322 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Binder Superfamily
Class Class 202

Cousin Family NamesSeedsMembers
Alpha-2A adrenergic receptor Ligand Brimonidine Family 3 6
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 9
Epidermal growth factor receptor ligand AGN-PC-07Q1HU family 4 17
Epidermal growth factor receptor ligand AGN-PC-076GVG family 8 1
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Epidermal growth factor receptor ligand AGN-PC-076GXM family 6 0
Metabotropic glutamate receptor 5 ligand SureCN3866791 family 2 10
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Epidermal growth factor receptor ligand (2R,3R)-3-[[4-(3-bromo... 3 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Epidermal growth factor receptor ligand AGN-PC-076GWD family 2 0
Epidermal growth factor receptor ligand (E)-N-[4-(3-bromoanili... 2 1
Epidermal growth factor receptor ligand N-[4-(3-bromoanilino)-... 2 0
Epidermal growth factor receptor ligand 4-Anilinopyrido[3,4-d]... 2 0
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Epidermal growth factor receptor ligand (E)-1-[4-(3-bromoanili... 9 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
Epidermal growth factor receptor ligand AGN-PC-078X9P family 4 0
LIM domain kinase 1 and LIM domain kinase 2 inhibitor (2S)-N'-... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432324 CHEMBL296168 Bioactive SureCN2996073
CFAMM00432323 CHEMBL474142 Bioactive AGN-PC-078X7K
CFAMM00432322 CHEMBL474143 Bioactive AGN-PC-078X7L

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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