CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1510
Family Name Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 inhibitor [4-[[4-[(E)-[1-[(4-fluorophenyl)methyl]-3-methyl-2,5-dioxoimidazolidin-4-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00324419 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 2417

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Histamine H3 receptor Ligand A-349821 Family 49 228
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Ectonucleotide pyrophosphatase/phosphodiesterase family member... 1 5


External ID

Functional Category

Molecule Name

CFAMM00324419 CHEMBL1802517 Bioactive [4-[[4-[(E)-[1-[(4-fluorophenyl)methyl]-3-methyl-2,5-dioxoimidazolidin-4-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid
CFAMM00324416 CHEMBL1802518 Bioactive [4-[[4-[(Z)-[1-[(4-fluorophenyl)methyl]-3-methyl-2,5-dioxoimidazolidin-4-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid
CFAMM00324409 CHEMBL1173671 Bioactive [4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid
CFAMM00324415 CHEMBL1802519 Bioactive [4-[[4-[(E)-[1-[(4-fluorophenyl)methyl]-2,5-dioxopyrrolidin-3-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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