CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15114
Family Name Prothrombin and Trypsin-1 inhibitor AGN-PC-073O5X family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00432375 Functional Category Bioactive
Superfamily Prothrombin and Trypsin-1 inhibitor AGN-PC-073O5X Superfamily
Class Class 3703

Cousin Family NamesSeedsMembers
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 10 5
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 11 4
Prostaglandin D2 receptor 2 ligand SureCN1713638 family 2 1
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 3 0
Growth hormone secretagogue receptor type 1 ligand N-benzyl-2-... 5 19


External ID

Functional Category

Molecule Name

CFAMM00432375 CHEMBL45062 Bioactive AGN-PC-073O5X
CFAMM00432378 CHEMBL44226 Bioactive AGN-PC-073O5W
CFAMM00432377 CHEMBL296737 Bioactive 2-[3-(benzylsulfonylamino)-6-methyl-2-oxopyridin-1-yl]-N-[[5-chloro-2-[2-(ethylamino)-2-oxoethoxy]phenyl]methyl]acetamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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