CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15116
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor (2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-phenoxyphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00432382 Functional Category Bioactive
Superfamily Matrix metalloproteinase-9 and 72 kDa type IV collagenase Binder Superfamily 6
Class Class 2185

Cousin Family NamesSeedsMembers
Apricoxib family 8 77
Indeglitazar family 3 39
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
Matrix metalloproteinase-14 and A disintegrin and metalloprote... 3 0
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
Macrophage metalloelastase inhibitor (2S)-3-methyl-2-[[8-[3-(t... 2 6
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 3
Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydr... 2 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432382 CHEMBL296817 Bioactive (2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-phenoxyphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid
CFAMM00432380 CHEMBL49499 Bioactive (2R)-2-[[5-[2-(4-butoxyphenyl)ethynyl]thiophen-2-yl]sulfonylamino]-3-(1H-indol-3-yl)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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