CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1513
Family Name Neuropeptide Y receptor type 5 ligand 2-[4-(benzenesulfonamido)piperidin-1-yl]-N-[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide family
No. of Seeds 2 No. of Other Members 27
Family Centroid CFAMM00324450 Functional Category Bioactive
Superfamily Prothrombin and P2X purinoceptor 7 Binder Superfamily
Class Class 3305

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 158
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Rho-associated protein kinase 1 Inhibitor Rho-kinase Inhibitor... 6 39
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Amg 423 family 7 47
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 11
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 5 10
Disintegrin and metalloproteinase domain-containing protein 17... 5 9
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04SK7R family 3 3
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
C-X-C chemokine receptor type 3 ligand (6aR,9R)-N-phenyl-4-(2-... 5 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 6 8
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 5 2
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... 4 8
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 2 4
Coagulation factor X and Anionic trypsin inhibitor Sulfonamido... 2 4
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 1 3
Prothrombin inhibitor N-[(2S)-3-(4-aminophenyl)-1-[4-(2-fluoro... 1 0
C-C chemokine receptor type 8 ligand ethyl 4-[[4-(pyridine-4-c... 2 1
P2X purinoceptor 7 inhibitor AGN-PC-015BSR family 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 2 0
Acetylcholinesterase inhibitor CHEMBL267591 family 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324450 CHEMBL117400 Bioactive 2-[4-(benzenesulfonamido)piperidin-1-yl]-N-[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide
CFAMM00324461 CHEMBL324311 Bioactive 2-[(3S)-3-(benzenesulfonamido)pyrrolidin-1-yl]-N-[6-fluoro-1-(pyridin-3-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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