CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15132
Family Name 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 1A ligand 4-(furan-3-yl)-2-(4-methylpiperazin-1-yl)-6-phenylpyrimidine family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00432467 Functional Category Bioactive
Superfamily Prelamin-A/C and Histamine H4 receptor Binder Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
Adenosine receptor A2a Ligand BIIB014 Family 26 92
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 3 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-(fur... 7 15
5-hydroxytryptamine receptor 2C Ligand 4-(piperazin-1-yl)furo[... 3 11
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Sodium-dependent serotonin transporter Inhibitor 4-furan-2-yl-... 2 10
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 1 0
Histamine H4 receptor and Histamine H3 receptor ligand SureCN6... 17 51
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 1
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 5 8
Adenosine kinase inhibitor 7-[(4aS,7aS)-6-benzyl-3,4,4a,5,7,7a... 2 1
Adenosine receptor A2a ligand 2-(furan-2-yl)-7-[3-[(4-phenylpi... 11 2
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Histamine H4 receptor ligand 8-fluoro-4-[(3R)-3-(methylamino)p... 6 1
Histamine H4 receptor and Histamine H3 receptor ligand 7-(fura... 2 2
Glycogen synthase kinase-3 beta inhibitor 2-(furan-3-yl)-N-[2-... 3 3
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
G1/S-specific cyclin-E1 and Cyclin-dependent kinase 2 inhibito... 1 4
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
5-hydroxytryptamine receptor 3A and Histamine H4 receptor liga... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 19 2
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 15 1
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 9 0
Dual specificity protein kinase CLK4 and Dual specificity tyro... 6 2
Dual specificity protein kinase CLK4 and Dual specificity prot... 3 6
Fatty-acid amide hydrolase 1 inhibitor (Z)-1-(4-pyrimidin-4-yl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432467 CHEMBL43434 Bioactive 4-(furan-3-yl)-2-(4-methylpiperazin-1-yl)-6-phenylpyrimidine
CFAMM00432466 CHEMBL42130 Bioactive AGN-PC-073O1Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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