CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15165
Family Name Caspase-1 inhibitor (3S)-3-[[(4S,7S)-7-[(2-fluorobenzoyl)amino]-6,10-dioxo-2,3,4,7,8,9-hexahydro-1H-pyridazino[1,2-a]diazepine-4-carbonyl]amino]-4-oxobutanoic acid family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00432657 Functional Category Bioactive
Superfamily Neutrophil elastase Inhibitor FK-706 Superfamily
Class Class 1231

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Integrin beta-3 Inhibitor Sibrafiban Family 4 6
Integrin beta-3 Inhibitor L-709780 Family 9 10
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 6 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7285564... 1 2
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-074AY6... 1 0
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-[... 8 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432659 CHEMBL415893 Bioactive (3S)-3-[[(4S,7S)-7-benzamido-6,10-dioxo-2,3,4,7,8,9-hexahydro-1H-pyridazino[1,2-a]diazepine-4-carbonyl]amino]-4-oxobutanoic acid
CFAMM00432658 CHEMBL324129 Bioactive (3S)-3-[[(4S)-7-benzamido-6,10-dioxo-2,3,4,7,8,9-hexahydro-1H-pyridazino[1,2-a]diazepine-4-carbonyl]amino]-4-oxobutanoic acid
CFAMM00432657 CHEMBL299288 Bioactive (3S)-3-[[(4S,7S)-7-[(2-fluorobenzoyl)amino]-6,10-dioxo-2,3,4,7,8,9-hexahydro-1H-pyridazino[1,2-a]diazepine-4-carbonyl]amino]-4-oxobutanoic acid
CFAMM00432660 CHEMBL325605 Bioactive (3S)-3-[[7-[(2-fluorobenzoyl)amino]-6,10-dioxo-2,3,4,7,8,9-hexahydro-1H-pyridazino[1,2-a]diazepine-4-carbonyl]amino]-4-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42566 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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