CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15177
Family Name Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ligand 1-[3-[3,3-bis(4-methylphenyl)-2,5-dioxopyrrolidin-1-yl]propyl]-4-(2-methylphenyl)piperidine-4-carbonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00432688 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor Binder Superfamily 3
Class Class 1062

Cousin Family NamesSeedsMembers
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Mu-type opioid receptor Ligand Diphenoxylate Family 5 6
Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 9
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 18
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 6
Histamine H3 receptor ligand [(3aR,6aR)-4-[4-[2-[(2R)-2-methyl... 6 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432687 CHEMBL62249 Bioactive AGN-PC-074B4S
CFAMM00432688 CHEMBL299914 Bioactive 1-[3-[3,3-bis(4-methylphenyl)-2,5-dioxopyrrolidin-1-yl]propyl]-4-(2-methylphenyl)piperidine-4-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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