CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15179
Family Name Purine nucleoside phosphorylase inhibitor SureCN6345422 family
No. of Seeds 9 No. of Other Members 11
Family Centroid CFAMM00321178 Functional Category Bioactive
Superfamily Purine nucleoside phosphorylase Binder Superfamily
Class Class 1306

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-(1h-imidazol-4-yl)be... 2 6
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Purine nucleoside phosphorylase inhibitor 7-[(3R,4S,5R)-3,4-di... 10 34
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 17 17
Purine nucleoside phosphorylase inhibitor 2-amino-7-[[(2S,4R)-... 5 0
Adenosine receptor A3 and Adenosine receptor A2a ligand 4-(5-b... 2 5
Purine nucleoside phosphorylase inhibitor 2-amino-6-benzyl-1,7... 3 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Lysine--tRNA ligase inhibitor 4-[[[2-(2-piperazin-1-ylpyridin-... 2 1
Serine/threonine-protein kinase Chk1 inhibitor 6-chloro-3-(1,3... 4 2
Purine nucleoside phosphorylase inhibitor 3-[(2S,3S,4R,5R)-3,4... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 1
Purine nucleoside phosphorylase inhibitor (3s)-3-(2-amino-4-hy... 2 0
Purine nucleoside phosphorylase inhibitor SureCN6353628 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432705 CHEMBL79410 Bioactive SureCN6351801
CFAMM00432696 CHEMBL55454 Bioactive SureCN9877738
CFAMM00432703 CHEMBL315570 Bioactive 3-(3-chlorophenyl)-3-(4-oxo-1,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)propanenitrile
CFAMM00432702 CHEMBL56540 Bioactive SureCN9217876
CFAMM00432693 CHEMBL82087 Bioactive SureCN9073768
CFAMM00432707 CHEMBL81839 Bioactive SureCN8631275

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26405 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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