CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15193
Family Name 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2A ligand 8-(3-phenoxypropyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00279952 Functional Category Bioactive
Superfamily Cellular tumor antigen p53 and Prelamin-A/C Binder Superfamily 10
Class Class 2070

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 3 67
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 28 91
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 8
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 2
D(2) dopamine receptor and Muscarinic acetylcholine receptor M... 1 0
Translocator protein inhibitor CHEMBL2332259 family 2 0
Nociceptin receptor and Mu-type opioid receptor ligand SureCN7... 13 22
Nociceptin receptor and Mu-type opioid receptor ligand N-ethyl... 8 3
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Histamine H3 receptor ligand AGN-PC-077MDJ family 2 1
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 1 0
Sodium- and chloride-dependent glycine transporter 1 and Mu-ty... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26179 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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