CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15195
Family Name D(1A) dopamine receptor and D(2) dopamine receptor ligand A31472 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00026886 Functional Category Bioactive
Superfamily Monoamine reuptake inhibitor Sertraline Sibutramine Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Zicronapine family 43 62
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and Sigma no... 1 4
Sodium-dependent dopamine transporter inhibitor N-[[(1S,3S,4R,... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
D(2) dopamine receptor ligand AGN-PC-041NNJ family 1 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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