CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15208
Family Name Sterol O-acyltransferase 1 inhibitor 1,1-bis[5-[[4,5-bis(4-methoxyphenyl)-1H-imidazol-2-yl]sulfanyl]pentyl]-3-propan-2-ylurea family
No. of Seeds 1 No. of Other Members 15
Family Centroid CFAMM00432853 Functional Category Bioactive with Natural Product
Superfamily TGF-beta receptor type-1 and Beta-lactamase Binder Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Tyrosine kinase Inhibitor PKI166 Family 17 198
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Aurora kinase A inhibitor SureCN208325 family 1 5
Casein kinase I isoform delta and Mitogen-activated protein ki... 3 18
Activated CDC42 kinase 1 inhibitor 5-(2-fluorophenyl)-N-[[(2S)... 5 0
Neuropeptide Y receptor type 5 ligand 6-ethylsulfonyl-2-(4-phe... 4 4
Arachidonate 15-lipoxygenase inhibitor SureCN14288120 family 3 12
Lysosomal Pro-X carboxypeptidase inhibitor 4-[6-[(2S)-2-(5,6-d... 2 2
Sterol O-acyltransferase 1 inhibitor SureCN9430680 family 7 3
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1H-benzimidaz... 3 2
Histamine H3 receptor ligand [4-[2-[2-(1H-imidazol-5-yl)ethyls... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432853 CHEMBL300883 Bioactive 1,1-bis[5-[[4,5-bis(4-methoxyphenyl)-1H-imidazol-2-yl]sulfanyl]pentyl]-3-propan-2-ylurea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27529 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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