CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15215
Family Name Thromboxane-A synthase inhibitor 7-[(2S,3R)-3-pyridin-3-yl-2-bicyclo[2.2.1]heptanyl]heptanoic acid family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00432875 Functional Category Bioactive
Superfamily Thromboxane-A synthase and C-C chemokine receptor type 5 Binder Superfamily
Class Class 240

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M4 Ligand Tropicamide Family 3 73
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor Cycl... 1 0
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 3 5
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 12
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase inhibit... 2 24
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 2 1
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase inhibit... 4 8
C-C chemokine receptor type 5 ligand AC1LA259 family 1 1
Thromboxane-A synthase inhibitor (Z)-2-bromo-3-[4-(pyridin-3-y... 1 0
Potassium voltage-gated channel subfamily A member 5 ligand AG... 4 0
Fatty-acid amide hydrolase 1 inhibitor [(1R)-1-[(3S)-2-oxo-1-p... 1 2
Pyridines and Derivatives Metabolite 4-Hydroxy-4-(3-pyridyl)-b... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00432875 CHEMBL301280 Bioactive 7-[(2S,3R)-3-pyridin-3-yl-2-bicyclo[2.2.1]heptanyl]heptanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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