CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1523
Family Name Acetylcholinesterase and Cholinesterase inhibitor 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-5-YL]HEXYL]-PHENANTHRIDINIUM family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00324554 Functional Category Bioactive
Superfamily Protein kinase C theta type and Protein kinase C delta type Binder Superfamily
Class Class 1666

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Sarcoplasmic/endoplasmic reticulum calcium ATPase inhibitor qu... 2 60
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
PF-4217903 family 14 65
D(4) dopamine receptor Ligand Fauc 113 Family 14 96
TGF-beta receptor type-1 Ligand 4-(3-pyridin-2-yl-1h-pyrazol-4... 3 63
TGF-beta receptor type-1 Ligand Naphthyridine Inhibitor Family 3 6
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(1h-1,2,3-triazol-5-... 3 12
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 2 1 2
Protein kinase C theta type and Protein kinase C delta type in... 16 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 33
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 6
Progesterone receptor and Mineralocorticoid receptor ligand AG... 6 1
Metabotropic glutamate receptor 5 ligand AGN-PC-075GBZ family 2 5
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 0
Mast/stem cell growth factor receptor Kit and Receptor-type ty... 8 3
D(4) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 1
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 6
Transient receptor potential cation channel subfamily V member... 1 0
TGF-beta receptor type-1 ligand N-(3-cyanophenyl)-2-[3-(6-meth... 4 5
TGF-beta receptor type-1 ligand 6-bromo-4-(2-(6-methylpyridin-... 1 3
TGF-beta receptor type-1 ligand SureCN373106 family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324554 CHEMBL117651 Bioactive 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-5-YL]HEXYL]-PHENANTHRIDINIUM
CFAMM00324556 CHEMBL540657 Bioactive 6-phenyl-5-[6-[1-[2-(1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]triazol-4-yl]hexyl]phenanthridin-5-ium-3,8-diamine;chloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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