CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1524
Family Name Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-prop-2-enylcarbamimidoyl)benzoyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]acetic acid family
No. of Seeds 7 No. of Other Members 15
Family Centroid CFAMM00324578 Functional Category Bioactive
Superfamily Integrin beta-3 Inhibitor SB-208651 Superfamily
Class Class 2096

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Urokinase-type plasminogen activator Inhibitor 6-(n-phenylcarb... 2 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Integrin beta-3 Inhibitor SB-208651 Family 9 28
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7345980... 4 6
Coagulation factor X and Trypsin-1 inhibitor SureCN6161266 family 2 28
Free fatty acid receptor 1 ligand AGN-PC-03ZC6J family 2 14
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-037CNR f... 5 8
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7502133 f... 4 7
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7102231 f... 3 8
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-073KEE f... 4 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7500077 f... 6 2
Integrin beta-3 and Integrin alpha-V inhibitor 3-[[[3-(diamino... 5 4
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-0BOW0P... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Tankyrase-2 inhibitor 3-chloro-4-(4-methyl-2-oxo-1H-quinolin-7... 1 2
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4


External ID

Functional Category

Molecule Name

CFAMM00324570 CHEMBL126485 Bioactive 2-[6-[(4-carbamimidoyl-2,6-difluorobenzoyl)amino]-1-oxo-3,4-dihydro-2H-naphthalen-2-yl]acetic acid
CFAMM00324576 CHEMBL126411 Bioactive AGN-PC-00F7B9
CFAMM00324567 CHEMBL8283 Bioactive 3-[3-[(4-carbamimidoylbenzoyl)amino]phenyl]propanoic acid
CFAMM00324563 CHEMBL130405 Bioactive 2-[7-[[4-(N'-propylcarbamimidoyl)benzoyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]acetic acid
CFAMM00324578 CHEMBL131593 Bioactive 2-[7-[[4-(N'-prop-2-enylcarbamimidoyl)benzoyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]acetic acid
CFAMM00324571 CHEMBL130892 Bioactive 2-[7-[[4-(N'-prop-2-ynylcarbamimidoyl)benzoyl]amino]-1,2,3,4-tetrahydronaphthalen-2-yl]acetic acid
CFAMM00324561 CHEMBL117662 Bioactive 2-[6-[(4-carbamimidoylbenzoyl)amino]-1-oxo-3,4-dihydro-2H-naphthalen-2-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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