CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15266
Family Name Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-[5-(6-chloro-1H-benzimidazol-2-yl)pyridin-2-yl]phenyl]cyclohexyl]acetic acid family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00433091 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Nociceptin receptor Binder Superfamily 2
Class Class 1016

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Tryptase Inhibitor Babim Family 12 90
Histamine H3 receptor Ligand SCH79687 Family 11 29
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Platelet-activating factor receptor ligand SureCN9523843 family 4 4
Adenosine receptor A3 ligand SureCN6627522 family 3 2
Lysosomal Pro-X carboxypeptidase inhibitor 2-amino-N-[(2S)-1-[... 11 16
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family 1 3
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family 3 1
Lysosomal Pro-X carboxypeptidase inhibitor N-[(1S)-1-(5,6-dich... 3 21
Lysosomal Pro-X carboxypeptidase inhibitor 1-[(2S)-2-(5,6-dich... 2 2
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Transient receptor potential cation channel subfamily V member... 4 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(7-aminop... 1 1
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 3 0
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
A disintegrin and metalloproteinase with thrombospondin motifs... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433091 CHEMBL3037924 Bioactive 2-[4-[4-[5-(6-chloro-1H-benzimidazol-2-yl)pyridin-2-yl]phenyl]cyclohexyl]acetic acid
CFAMM00433092 CHEMBL3037925 Bioactive 2-[4-[4-[5-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]pyridin-2-yl]phenyl]cyclohexyl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543