CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15287
Family Name Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 ligand AC1NS6DH family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00389316 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 1 and Mitogen-activated protein kinase 3 Inhibitor Purvalanol Superfamily
Class Class 1173

Cousin Family NamesSeedsMembers
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Reverse transcriptase Inhibitor IDX899 Family 2 118
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
D(4) dopamine receptor Ligand L-745,870 Family 30 205
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
DNA gyrase subunit B inhibitor 2-chloro-6-[4-[(3,4-dichloro-5-... 1 3
Coagulation factor X inhibitor SureCN8289965 family 4 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 1
Epidermal growth factor receptor ligand AC1NS6CH family 1 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433207 CHEMBL304271 Bioactive AC1NS6DK
CFAMM00433204 CHEMBL69629 Bioactive AC1NS6CQ
CFAMM00433210 CHEMBL69358 Bioactive AC1NS6DE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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