CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15291
Family Name Granzyme B and Caspase-3 inhibitor CHEMBL304368 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00433223 Functional Category Bioactive
Superfamily Caspase-3 and Caspase-8 Binder Superfamily
Class Class 348

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfany... 7 23
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor (2S)-2-[[(3R)-5-(carbo... 6 4
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Caspase-8 and Caspase-3 inhibitor (3S)-3-[[(2S)-4-methyl-2-[[2... 3 2
Caspase-3 inhibitor CHEMBL420407 family 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor 3-[(3S)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433221 CHEMBL428244 Bioactive CHEMBL428244
CFAMM00433223 CHEMBL304368 Bioactive CHEMBL304368

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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