CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM153
Family Name Dual specificity mitogen-activated protein kinase kinase 1 inhibitor AGN-PC-03EU4R family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00308123 Functional Category Bioactive
Superfamily Platelet-derived growth factor receptor alpha and Platelet-derived growth factor receptor beta Ligand RPR-101511 Superfamily
Class Class 2018

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
Epidermal growth factor receptor and Receptor tyrosine-protein... 16 89
Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 67 130
Tivozanib family 4 6
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Platelet-derived growth factor receptor alpha and Platelet-der... 2 9
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Dual specificity mitogen-activated protein kinase kinase 1 inh... 10 54
3-phosphoinositide-dependent protein kinase 1 and Ribosomal pr... 10 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Proto-oncogene tyrosine-protein kinase Src inhibitor SureCN525... 8 8
Vascular endothelial growth factor receptor 2 and Vascular end... 3 3
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS5MA ... 3 4
Platelet-derived growth factor receptor beta ligand AGN-PC-075... 3 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Proto-oncogene tyrosine-protein kinase Src inhibitor AC1NS94Q ... 6 0
Hepatocyte growth factor receptor ligand 1-[(E)-(2,4-difluorop... 2 0
Vascular endothelial growth factor receptor 2 and Tyrosine-pro... 4 0
Vascular endothelial growth factor receptor 2 and Platelet-der... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 5 2
Macrophage colony-stimulating factor 1 receptor ligand 4-(3-ch... 5 4
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 7
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308130 CHEMBL318326 Bioactive 3-cyanoquinoline, 10
CFAMM00308123 CHEMBL288081 Bioactive AGN-PC-03EU4R
CFAMM00308129 CHEMBL102786 Bioactive AGN-PC-074U5J
CFAMM00308122 CHEMBL29714 Bioactive 3-cyanoquinoline, 9
CFAMM00308127 CHEMBL30359 Bioactive AGN-PC-03EU2N

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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