CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1531
Family Name Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-quinolin-3-yl-4-[1-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoyl]piperidin-4-yl]butanoic acid family
No. of Seeds 6 No. of Other Members 8
Family Centroid CFAMM00324628 Functional Category Bioactive
Superfamily Integrin alpha-V and Integrin beta-3 Binder Superfamily 2
Class Class 898

Cousin Family NamesSeedsMembers
Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Endothelin B receptor Ligand IRL-2500 Family 34 87
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03RR5Q f... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor methyl (3S)-3-(... 12 13
Coagulation factor X inhibitor (2S)-(3'-AMIDINO-3-BIPHENYL)-5-... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 fa... 8 32
Integrin alpha-V and Integrin beta-5 inhibitor SureCN6563167 f... 2 10
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family 13 8
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
B1 bradykinin receptor ligand AGN-PC-005XAO family 3 17
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-(benzene... 3 2
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN8335217 f... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00BBPN f... 2 3
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2833591 f... 4 6
Integrin beta-3 and Integrin alpha-V inhibitor SureCN2842307 f... 4 0
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00IW9E f... 3 0
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-... 7 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 1 5
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[3-(2... 4 2
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[4-(... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3S)-3-[[2-[(... 3 1
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-3-[4-[4-[[... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00324628 CHEMBL186616 Bioactive (3R)-3-quinolin-3-yl-4-[1-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoyl]piperidin-4-yl]butanoic acid
CFAMM00324634 CHEMBL117964 Bioactive AGN-PC-03PSVZ
CFAMM00324633 CHEMBL184663 Bioactive AGN-PC-075G1I
CFAMM00324631 CHEMBL189201 Bioactive SureCN6359531

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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