CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15324
Family Name Thymidylate synthase inhibitor 3-(methylamino)-5,6-dihydro-4H-benzo[f]quinazolin-1-one family
No. of Seeds 2 No. of Other Members 19
Family Centroid CFAMM00433428 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Phospholipase A2 Binder Superfamily
Class Class 3211

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Methionine--tRNA ligase, cytoplasmic and Methionine--tRNA liga... 8 6
Methionine--tRNA ligase inhibitor 2-({3-[(3,5-Dichlorobenzyl)a... 5 7
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Methionine--tRNA ligase inhibitor 2-[3-[(6-ethyl-8-iodo-1,2,3,... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor 4-[1-[3-(4-oxo-1H-qui... 1 3
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Thymidylate synthase inhibitor 6-[[4-(benzenesulfonyl)-N-prop-... 12 6
Transient receptor potential cation channel subfamily V member... 4 6
Transient receptor potential cation channel subfamily V member... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433428 CHEMBL305610 Bioactive 3-(methylamino)-5,6-dihydro-4H-benzo[f]quinazolin-1-one
CFAMM00433414 CHEMBL75606 Bioactive 3-(benzylamino)-7-fluoro-4H-benzo[f]quinazolin-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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