CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM15326
Family Name Dihydrofolate reductase inhibitor 5-[[4-(2,4-dichlorophenyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]pyrimidine-2,4-diamine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00433445 Functional Category Bioactive
Superfamily Dual specificity protein kinase CLK1 and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 377

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Dual specificity protein kinase CLK1 and Dual specificity prot... 2 14
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00433445 CHEMBL305656 Bioactive 5-[[4-(2,4-dichlorophenyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]methyl]pyrimidine-2,4-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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